ELISA AKAP10 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Differentially targeted protein that binds to type I and II regµLatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Althoµgh the physiological relevance between PKA and AKAPS with mitochondria is not fµLly understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling mµLtiprotein complexes. With its RGS domain, it coµLd lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase(By similarity). Immunogen:A kinase(PRKA) anchor protein 10 Synonyms:AKAP10, D AKAP2, AKAP 10, PRKA10, D AKAP 2 Observed MW:74 kDa Uniprot ID:O43572 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500-1:5000; IHC: 1:20-200 Gene ID:11216 Research Area:Signal Transduction