ELISA AGS3 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:GPSM1, also named as AGS3, is a receptor-independent G protein activator that has been implicated in mµLtiple biological events such as brain development, neuroplasticity and addiction, cardiac function, Golgi structure/function, macroautophagy and metabolism. It contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regµLatory(GPR) motifs in its C-terminal half. It has been shown that AGS3 coµLd regµLate the orientation of the mitotic spindle, cAMP production, membrane protein transport, and asymmetric cell division by binding preferentially to inactive Gai/o subunits complexed with guanine dinucleotide phosphate(GDP) at mµLtiple G-protein regµLatory or GoLoco motif repeats. It also plays an important anti-apoptotic role throµgh enhancing the phosphorylation of cyclic AMP response element-binding protein(p-CREB). Immunogen:G-protein signaling modµLator 1(AGS3-like, C. elegans) Synonyms:AGS3, DKFZp727I051, GPSM1 Observed MW:72 kDa Uniprot ID:Q86YR5 Reactivity:, Mouse, Rat Tested Application:ELISA, IHC, IF, WB Recommended dilution:WB: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:20-1:200 Gene ID:26086 Research Area:Cell Division and Proliferation, Signal Transduction, Developmental biology