ELISA Adenylosuccinate lyase anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:ADSL(adenylosuccinate lyase) is also named as AMPS, ASase, ASL and belongs to the lyase 1 family. It is an enzyme involved in 2 pathways of purine nucleotide metabolism and catalyzes cleavage of succinyl groups to yield fumarate(PMID:18524658). Defects in ADSL are the cause of adenylosuccinase deficiency(ADSL deficiency). In s, mutations in ADSL lead to an inborn error of metabolism originally characterized by developmental delay, often with autistic features(PMID:20884265)..The ADSL enzymatic activity is reduced in lymphocytes and red blood cells of the patient with severe psychomotor retardation(PMID:9545543). It has 2 isoforms produced by alternative splicing. Immunogen:adenylosuccinate lyase Synonyms:Adenylosuccinase, adenylosuccinate lyase, ADSL, AMPS, ASASE, ASL Observed MW:55 kDa Uniprot ID:P30566 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IF, FC Recommended dilution:WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100 Gene ID:158 Research Area:Metabolism