ELISA CD46 anti-

Quantity :50µL Clone Number:7D12 Aliases:Membrane cofactor protein (TLX) (Trophoblast leukocyte common antigen) (CD antigen CD46), CD46, MCP MIC10 Product Type:Recombinant Antibody Immunogen Species:Homo sapiens () UniProt ID:P15529 Immunogen:A syntheQuantityd peptide derived from CD46 Raised in: Reactivity: Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200 Background:Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimµLatory factor for T-cells which induces the differentiation of CD4+ into T-regµLatory 1 cells. T-regµLatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thoµght to prevent autoimmunity. Clonality:Monoclonal Isotype:Rabbit IgG Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CD46 Research Areas:Immunology