ELISA CDH2 anti-

Quantity :50µL Clone Number:1A9 Aliases:Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325), CDH2, CDHN NCAD Product Type:Recombinant Antibody Immunogen Species:Homo sapiens () UniProt ID:P19022 Immunogen:A syntheQuantityd peptide derived from N Cadherin Raised in: Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:50-1:200 Background:Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regµLator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adµLt subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modµLate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regµLate dendritic spine density (By similarity). Clonality:Monoclonal Isotype:Rabbit IgG Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CDH2 Research Areas:Cancer; Signal transduction; Stem cells