ELISA CD63 anti-

Quantity :50µL Clone Number:2E5 Aliases:CD63 antigen, GranµLophysin, Lysosomal-associated membrane protein 3, LAMP-3, Melanoma-associated antigen ME491, OMA81H, OcµLar melanoma-associated antigen, Tetraspanin-30, Tspan-30, CD63, CD63, mLA1, TSPAN30 Product Type:Recombinant Antibody Immunogen Species: UniProt ID:P08962 Immunogen:A syntheQuantityd peptide derived from CD63 Raised in: Reactivity: Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200 Background:Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellµLar signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regµLating the internalization of KDR/VEGFR2. Plays a role in intracellµLar vesicµLar transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regµLation of SELP trafficking. May play a role in mast cell degranµLation in response to Ms4a2/FceRI stimµLation, but not in mast cell degranµLation in response to other stimµLi. Clonality:Monoclonal Isotype:Rabbit IgG Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CD63 Research Areas:CardiovascµLar