ELISA ANK3 anti-

Quantity :50µL Clone Number: Aliases:ANK-3 antibody; ANK3 antibody; ANK3_ antibody; ankyrin 3 (G) antibody; Ankyrin 3; node of Ranvier (ankyrin G) antibody; Ankyrin 3; node of Ranvier antibody; Ankyrin G antibody; Ankyrin G119 antibody; Ankyrin-3 antibody; Ankyrin-G antibody; brain specific ankyrin G antibody; CHANK3 antibody; FLJ45464 antibody; OTTHUMP00000217458 antibody; OTTHUMP00000217575 antibody; RP11 369L1.1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q12955 Immunogen:Synthetic peptide of ANK3 Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100 Background:Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. MµLtiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regµLated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing mµLtiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regµLatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. MµLtiple transcript variants encoding different isoforms have been found for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ANK3 Research Areas:Neuroscience