ELISA CDK5R1 anti-

Quantity :100µL Clone Number: Aliases:CD5R1_ antibody; CDK5 activator 1 antibody; CDK5P35 antibody; CDK5R antibody; CDK5R1 antibody; Cyclin dependent kinase 5 regµLatory subunit 1 antibody; Cyclin-dependent kinase 5 activator 1 antibody; Cyclin-dependent kinase 5 regµLatory subunit 1 antibody; NCK 5A antibody; Neuronal CDK5 activator antibody; p23 antibody; p25 antibody; p35 antibody; RegµLatory partner for CDK5 kinase antibody; Tau protein kinase II 23 kDa subunit antibody; TPKII regµLatory subunit antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q15078 Immunogen:SyntheQuantityd peptide derived from internal of CDK5R1. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IF; WB:1:500-1:3000, IF:1:100-1:500 Background:p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regµLation of the circadian clock by modµLating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regµLates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellµLar distribution. Tsai L.-H., Nature 371:419-423(1994). Patrick G.N., Nature 402:615-622(1999). Kesavapany S., J. Neurosci. 24:4421-4431(2004). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CDK5R1 Research Areas:Epigenetics and Nuclear Signaling?Neuroscience;Cell biology;Signal transduction