ELISA ANKRD28 anti-

Quantity :50µL Clone Number: Aliases:ANKRD28 antibody; KIAA0379Serine/threonine-protein phosphatase 6 regµLatory ankyrin repeat subunit A antibody; PP6-ARS-A antibody; Serine/threonine-protein phosphatase 6 regµLatory subunit ARS-A antibody; Ankyrin repeat domain-containing protein 28 antibody; Phosphatase interactor targeting protein hnRNP K antibody; PITK antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O15084 Immunogen:Synthetic peptide of ANKRD28 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000 Background:Putative regµLatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modµLate HNRPK phosphorylation. ANKRD28 selectively regµLated phosphorylation of hnRNP-K at ser284, an effect that was enhanced in vivo by an S1013A/S1017A double mutant, sµggesting that ANKRD28 targets PP1 in a regµLated manner to dephosphorylate hnRNP-K selectively at ser284. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ANKRD28 Research Areas:Epigenetics and Nuclear Signaling;Cell biology;Signal transduction