ELISA METTL14 Antibody, FITC
Quantity :50µg
Clone Number:
Aliases:KIAA1627 antibody; MET14_ antibody; Methyltransferase like 14 antibody; Methyltransferase-like protein 14 antibody; METTL14 antibody; N6-adenosine-methyltransferase subunit METTL14 antibody; OTTHUMP00000219837 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q9HCE5
Immunogen:Recombinant N6-adenosine-methyltransferase subunit METTL14 protein (24-206AA)
Raised in:Rabbit
Reactivity:
Tested Applications:
Background:N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regµLator of the circadian clock and differentiation of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5\\\'-[AG]GAC-3\\\' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing, processing and mRNA stability (PubMed:24316715, PubMed:24407421, PubMed:25719671). M6A regµLates the length of the circadian clock: acts as a early pace-setter in the circadian loop. M6A also acts as a regµLator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts resµLts in transcript destabilization (By similarity).
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:METTL14
Research Areas:Cell biology
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