ELISA RUBCN Antibody, Biotin

Quantity :50µL Clone Number: Aliases:Baron antibody; Beclin 1 associated RUN domain containing protein antibody; Beclin-1 associated RUN domain containing protein antibody; hypothetical protein LOC9711 antibody; Kiaa0226 antibody; OTTHUMP00000208021 antibody; OTTHUMP00000208023 antibody; OTTHUMP00000208024 antibody; RUBIC_ antibody; Rubicon antibody; RUN domain and cysteine rich domain containing, Beclin 1 interacting protein antibody; Run domain Beclin 1 interacting and cystein rich containing protein antibody; Run domain Beclin-1 interacting and cysteine-rich containing protein antibody; RUN domain protein as Beclin 1 interacting and cysteine rich containing antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q92622 Immunogen:Recombinant Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (518-733AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Inhibits PIK3C3 activity; under basal conditions negatively regµLates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regµLates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regµLates Rab7 activation (PubMed:20974968, PubMed:21062745). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RUBCN Research Areas:Cancer; CardiovascµLar; Cell biology; Metabolism; Signal transduction