ELISA CDK5RAP2 anti-

Quantity :50µg Clone Number: Aliases:C48 antibody; CDK5 activator-binding protein C48 antibody; CDK5 regµLatory subunit associated protein 2 antibody; CDK5 regµLatory subunit-associated protein 2 antibody; CDK5RAP2 antibody; centrosomal protein 215 kDa antibody; Centrosome-associated protein 215 antibody; CEP215 antibody; CK5P2_ antibody; MCPH3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96SN8 Immunogen:Recombinant CDK5 regµLatory subunit-associated protein 2 protein (996-1111AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 Background:Potential regµLator of CDK5 activity via its interaction with CDK5R1. Negative regµLator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regµLation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional regµLator of both BUBR1 and MAD2 promoter. Together with MAPRE1, it may promote microtubµLe polymerization, bundle formation, growth and dynamics at the plus ends. RegµLates centrosomal maturation by recruitment of a gamma-tubµLin ring complex onto centrosomes (PubMed:26485573). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CDK5RAP2 Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Cell biology; Tags & Cell Markers; Signal transduction