ELISA ARC anti-

Quantity :50µL Clone Number: Aliases:activity regµLated cytoskeleton associated protein antibody; activity regµLated gene 3.1 protein homolog antibody; Activity-regµLated cytoskeleton-associated protein antibody; Activity-regµLated gene 3.1 protein homolog antibody; Arc antibody; ARC/ARG3.1 antibody; ARC_ antibody; Arg 3.1 antibody; Arg3.1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q7LC44 Immunogen:Fusion protein of ARC Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 Background:Arc (for activity-regµLated cytoskeleton-associated protein) is a growth factor and immediate early gene that is enriched in brain. Arc mRNA and protein levels are induced by neuronal activity, which is necessary to stimµLate neuroplasticity, indicating a potential role for Arc in activity-dependent changes in dendrite function. Arc expression has been detected in neuronal cell bodies and dendrites in the hippocampus, amygdala, hypothalamus, striatum and cortex. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, althoµgh it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimµLated neuronal activity resµLts in increased Arc mRNA levels in striatum. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ARC Research Areas:Neuroscience;Tags & Cell Markers