ELISA CAND1 Antibody, HRP

Quantity :50µg Clone Number: Aliases:CAND 1 antibody; Cand1 antibody; CAND1_ antibody; CµLlin associated and neddylation dissociated 1 antibody; CµLlin associated and neddylation dissociated protein 1 antibody; CµLlin associated NEDD8 dissociated protein 1 antibody; CµLlin-associated and neddylation-dissociated protein 1 antibody; CµLlin-associated NEDD8-dissociated protein 1 antibody; DKFZP434M1414 antibody; FLJ10114 antibody; FLJ10929 antibody; FLJ38691 antibody; FLJ90441 antibody; KIAA0829 antibody; p120 CAND1 antibody; TATA binding protein interacting protein 120A antibody; TBP interacting protein antibody; TBP interacting protein of 120 kDa A antibody; TBP Interacting Protein TIP120A antibody; TBP-interacting protein 120A antibody; TBP-interacting protein of 120 kDa A antibody; TIP120 antibody; TIP120 protein antibody; TIP120A antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q86VP6 Immunogen:Recombinant CµLlin-associated NEDD8-dissociated protein 1 protein (1150-1230AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Key assembly factor of SCF (SKP1-CµL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellµLar repertoire of SCF complexes. Acts as a F-box protein exchange factor. The exchange activity of CAND1 is coupled with cycles of neddylation conjµgation: in the deneddylated state, cµLlin-binding CAND1 binds CµL1-RBX1, increasing dissociation of the SCF complex and promoting exchange of the F-box protein. Probably plays a similar role in other cµLlin-RING E3 ubiquitin ligase complexes. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CAND1 Research Areas:Epigenetics and Nuclear Signaling