ELISA ALDOB anti-

Quantity :100µL Clone Number: Aliases:ALDB antibody; ALDO B antibody; ALDO2 antibody; ALDOB antibody; ALDOB_ antibody; Aldolase 2 antibody; Aldolase B antibody; Aldolase B fructose bisphosphate antibody; Aldolase2 antibody; AldolaseB antibody; EC 4.1.2.13 antibody; Fructose bisphosphate aldolase B antibody; Fructose-bisphosphate aldolase B antibody; Liver type aldolase antibody; Liver-type aldolase antibody; MS1077 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P05062 Immunogen:SyntheQuantityd peptide derived from internal of ALDOB. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regµLated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adµLt muscle where it can be as much as 5% of total cellµLar protein. In adµLt liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. Paolella G., Nucleic Acids Res. 12:7401-7410(1984). Sakakibara M., Nucleic Acids Res. 13:5055-5069(1985). Rottmann W.H., Proc. Natl. Acad. Sci. U.S.A. 81:2738-2742(1984). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ALDOB Research Areas:Cancer;Metabolism;Signal transduction