ELISA ARHGEF5 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:ARHG5_ antibody; ARHGEF 5 antibody; ARHGEF5 antibody; DKFZp686N1969 antibody; ephexin 3 antibody; Ephexin-3 antibody; GEF 5 antibody; GEF5 antibody; Guanine nucleotide regµLatory protein TIM antibody; Oncogene TIM antibody; P60 antibody; p60 TIM antibody; Rho guanine nucleotide exchange factor (GEF) 5 antibody; Rho guanine nucleotide exchange factor 5 antibody; TIM 1 antibody; TIM antibody; TIM1 antibody; Transforming immortalized mammary oncogene antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q12774 Immunogen:Recombinant Rho guanine nucleotide exchange factor 5 protein (433-507AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624). Strongly activates RHOA (PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity). Involved in regµLation of cell shape and actin cytoskeletal organization (PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653). Required for SRC-induced podosome formation (By similarity). Involved in positive regµLation of immature dendritic cell migration (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ARHGEF5 Research Areas:Signal transduction