ELISA CBX3 Antibody, FITC

Quantity :50µg Clone Number: Aliases:CBX 3 antibody; CBX3 antibody; CBX3_ antibody; Chromobox homolog 3 (HP1 gamma homolog; Drosophila) antibody; Chromobox homolog 3 antibody; Chromobox protein homolog 3 antibody; GAMMA antibody; HECH antibody; Heterochromatin like protein 1 antibody; Heterochromatin protein 1 homolog gamma antibody; Heterochromatin protein HP1 gamma antibody; HP1 gamma antibody; HP1 gamma homolog antibody; HP1Hs gamma antibody; Modifier 2 protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13185 Immunogen:Recombinant Chromobox protein homolog 3 protein (10-122AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at \'Lys-9\', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane throµgh its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore throµgh interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state throµgh H3 \'Lys-9\' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CBX3 Research Areas:Epigenetics and Nuclear Signaling