ELISA ADD1 (Ab-726) anti-

Quantity :100µL Clone Number: Aliases:ADD A antibody; ADD1 antibody; ADDA antibody; ADDA_ antibody; Adducin 1 (alpha) antibody; Alpha adducin antibody; Alpha-adducin antibody; Erythrocyte adducin alpha subunit antibody; Erythrocyte adducin subunit alpha antibody; MGC3339 antibody; MGC44427 antibody; OTTHUMP00000151163 antibody; OTTHUMP00000151164 antibody; OTTHUMP00000151165 antibody; OTTHUMP00000218664 antibody; OTTHUMP00000218665 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P35611 Immunogen:Peptide sequence around aa.724~728 (T-P-S-F-L) derived from ADD1. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200 Background:Adducins are a family of cytoskeleton proteins encoded by three genes (a, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. a- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. a- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodµLin and is a substrate for protein kinases A and C. Alternative splicing resµLts in mµLtiple variants encoding distinct isoforms; however, not all variants have been fµLly described. Pariser H, et al. Proc Natl Acad Sci USA 2005 Aµg 30; 102(35): 12407-12 Tamaru S, et al. Biochem Biophys Res Commun 2005 JµL 01; 332(2): 347-51 Barkalow KL, et al. J Cell Biol 2003 May 12; 161(3): 557-70 Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ADD1 Research Areas:Tags & Cell Markers;Signal transduction