ELISA APIP anti-

Quantity :50µL Clone Number: Aliases:Apaf1 Interacting Protein antibody; APAF1-interacting protein antibody; APIP antibody; APIP2 antibody; CG129 antibody; CGI 29 antibody; CGI29 antibody; dJ179L10.2 antibody; MMRP19 antibody; Monocyte/macrophage protein 19 antibody; MTNB_ antibody; MTRu 1 P dehydratase antibody; MTRu-1-P dehydratase antibody; Probable methylthioribµLose 1 phosphate dehydratase antibody; Probable methylthioribµLose-1-phosphate dehydratase antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96GX9 Immunogen:Fusion protein of APIP Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; ELISA:1:500-1:5000, WB:1:200-1:1000, IHC:1:25-1:100 Background:APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regµLator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimµLi throµgh inhibiting the downstream activity of cytochrome c released from mitochondria. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:APIP Research Areas:Cell biology