ELISA Phospho-XIAP (Ser87) anti-

Quantity :100µL Clone Number: Aliases:AP 13 antibody; API3 antibody; Apoptosis Inhibitor 3 antibody; BacµLoviral IAP repeat containing 4 antibody; BacµLoviral IAP Repeat Containing Protein 4 antibody; BacµLoviral IAP repeat-containing protein 4 antibody; BIRC 4 antibody; BIRC4 antibody; E3 ubiquitin-protein ligase XIAP antibody; hIAP-3 antibody; hIAP3 antibody; HILP antibody; IAP 3 antibody; IAP like protein antibody; IAP-3 antibody; IAP-like protein antibody; IAP3 antibody; ILP 1 antibody; ILP antibody; ILP1 antibody; Inhibitor of apoptosis protein 3 antibody; Inhibitor of Apoptosis X Linked antibody; Mammalian IAP Homologue A antibody; MIHA antibody; X linked IAP antibody; X linked inhibitor of apoptosis antibody; X linked inhibitor of apoptosis E3 ubiquitin protein ligase antibody; X linked inhibitor of apoptosis protein antibody; X-linked IAP antibody; x-linked inhibitor of apopotosis proteins antibody; X-linked inhibitor of apoptosis protein antibody; Xiap antibody; XIAP_ antibody; XLP2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P98170 Immunogen:Peptide sequence around phosphorylation site of serine87(K-V-S(p)-P-N) derived from XIAP Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:1000 Background: MµLti-functional protein which regµLates not only caspases and apoptosis, but also modµLates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state. Huang X, Wu Z, Mei Y, Wu M (2013)EMBO J 32, 2204-16. Bornhauser BC, et al. (2007) Blood 110, 2084-91.Dan HC, et al. (2004)J Biol Chem 279, 5405-12. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:XIAP Research Areas:Cancer;Cell biology;Metabolism