ELISA C3 anti-

Quantity :50µg Clone Number: Aliases:C3Complement C3 antibody; HSE-MSF) [Cleaved into: Complement C3 beta chain; C3-beta-c antibody; C3bc); Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimµLating protein antibody; ASP antibody; C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2] antibody Product Type:Polyclonal Antibody Immunogen Species:Mus muscµLus (Mouse) UniProt ID:P01027 Immunogen:Recombinant Mouse Complement C3 protein (1321-1663AA) Raised in:Rabbit Reactivity:Mouse, Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:5000 Background:C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascµLar permeability and causes histamine release from mast cells and basophilic leukocytes. The short isoform hasB-cell stimµLatory activity. Acylation stimµLating protein: adipogenic hormone that stimµLates triglyceride (TG) synthesis and glucose transport in adipocytes, regµLating fat storage and playing a role in postprandial TG clearance. Appears to stimµLate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:C3 Research Areas:Immunology