ELISA FPR3 anti-

Quantity :50µL Clone Number: Aliases:FmL2_ antibody; FmLP related receptor II antibody; FmLP-R-II antibody; FmLP-related receptor II antibody; FmLPY antibody; Formyl peptide receptor 3 antibody; Formyl peptide receptor like 2 antibody; Formyl peptide receptor-like 2 antibody; FPR3 antibody; FPR3_ antibody; FPRH1 antibody; FPRH2 antibody; FPRL2 antibody; Lipoxin A4 receptor antibody; LXA4 R antibody; Lxa4r antibody; N formyl peptide receptor 3 antibody; N-formyl peptide receptor 3 antibody; RGD1566044 antibody; RmLP-R-I antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P25089 Immunogen:Synthetic peptide of FPR3 Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100 Background:The N-formyl peptide receptor (FPR) family is comprised of three members, FPR, FPR3 (also designated FPRL1, lipoxin A4 receptor, FPRH1 or FPR2) and FPR like-2 (FPRL2), all of which are chemotactic G protein-coupled receptors that contain seven transmembrane domains. These receptors are found on the surface of phagocytic leukocytes, such as neutrophils and monocytes, and each family member contains specific residues, which are responsible for determining its ligand specificity. FPR3 is a promiscuous receptor that binds to several ligands, including lipoxin A4, N-formyl-methionyl-leucyl-phenylalanine (fmLP), serum amyloid A (SAA), prion peptide and the 42 amino acid form of beta amyloid. Upon activation, FPR3 induces migration and calcium mobilization in monocytes and neutrophils and is involved in inflammatory and host defense responses. FPR3 may mediate inflammation in prion and Alzheimer’s diseases, which makes it a potential target for therapeutic agents. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:FPR3 Research Areas:Signal transduction