ELISA CASTOR2 Antibody, HRP

Quantity :50µL Clone Number: Aliases:CASTOR2 antibody; CellµLar arginine sensor for mTORC1 protein 2 antibody; GATL2_ antibody; GATS-like protein 2 antibody; GATSL2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:A6NHX0 Immunogen:Recombinant Cytosolic arginine sensor for mTORC1 subunit 2 protein (82-329AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Functions as a negative regµLator of the TORC1 signaling pathway throµgh the GATOR complex. As part of homodimers or heterodimers with CASTOR1, directly binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Does not directly bind arginine, but binding of arginine to CASTOR1 disrupts the interaction of CASTOR2-containing heterodimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CASTOR2 Research Areas:Others