ELISA CD207 anti-

Quantity :50µL Clone Number: Aliases:C type lectin domain family 4 member K antibody; C-type lectin domain family 4 member K antibody; CD 207 antibody; CD207 antibody; CD207 antigen antibody; CD207 antigen; langerin antibody; CD207 molecµLe antibody; CLC4K_ antibody; CLEC 4K antibody; CLEC4K antibody; Langerhans cell specific c type lectin antibody; Langerin antibody; RGD1565913 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UJ71 Immunogen:Fusion protein of CD207 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 Background:The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granµLes, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granµLes and providing access to a nonclassical antigen-processing pathway. Mutations in this gene resµLt in Birbeck granµLes deficiency or loss of sµgar binding activity. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CD207 Research Areas:Metabolism;Signal transduction