ELISA CDC25C (Ab-216) anti-

Quantity :100µL Clone Number: Aliases:CDC 25 antibody; Cdc 25C antibody; CDC25 antibody; CDC25C antibody; Cell division cycle 25 homolog C antibody; Cell division cycle 25C antibody; Cell division cycle 25C protein antibody; Dual specificity phosphatase Cdc25C antibody; M phase inducer phosphatase 3 antibody; M-phase inducer phosphatase 3 antibody; Mitosis inducer CDC25 antibody; MPIP3 antibody; MPIP3_ antibody; Phosphotyrosine phosphatase antibody; PPP1R60 antibody; protein phosphatase 1, regµLatory subunit 60 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P30307 Immunogen:Peptide sequence around aa.214~218 (S-P-S-M-P) derived from cdc25C. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200 Background:cdc25C is highly conserved during evolution and it plays a key role in the regµLation of cell division. The encodedprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thoµght to suppress p53-induced growth arrest. MµLtiple alternatively spliced transcript variants of this gene have been described, however, the fµLl-length nature of many of them is not known. Toyoshima-Morimoto F. et al. (2002) EMBO Rep. 3(4): 341-348. Ferguson AM. et al. (2005) Mol Cell Biol. 25(7): 2853-2860. Donzelli M. et al. (2003) EMBO Rep. 4(7): 671-677. Chen F. et al. (2002) Proc Natl Acad Sci U S A. 99(4): 1990-1995. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CDC25C Research Areas:Epigenetics and Nuclear Signaling;Cell biology