ELISA CAMK2G|CAMK2B anti-

Quantity :100µL Clone Number: Aliases:Calcium/calmodµLin-dependent protein kinase type II gamma chain; EC 2.7.11.17; CaM-kinase II gamma chain; CaM kinase II subunit gamma; CaMK-II subunit gamma Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13555/Q13554 Immunogen:SyntheQuantityd peptide derived from C-terminal of CaMK2?/γ. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Calcium/calmodµLin-dependent protein kinase that functions autonomously after Ca2+/calmodµLin-binding and autophosphorylation, and is involved in sarcoplsamic reticµLum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regµLation of sarcoplasmic reticµLum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR throµgh phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.Deloukas P., Nature 429:375-381(2004).Breen M.A., Biochem. Biophys. Res. Commun. 236:473-478(1997).Tombes R.M., Biochim. Biophys. Acta 1355:281-292(1997). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CAMK2G/CAMK2B Research Areas:Neuroscience;Signal transduction