ELISA CD2AP anti-

Quantity :50µL Clone Number: Aliases:Adapter protein CMS antibody; AL024079 antibody; C78928 antibody; Cas ligand with mµLtiple SH3 domains antibody; CD2 associated protein antibody; CD2-associated protein antibody; CD2AP antibody; CD2AP_ antibody; CMS antibody; Mesenchyme to epithelium transition protein with SH3 domains 1 antibody; METS 1 antibody; Mets1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y5K6 Immunogen:Synthetic peptide of CD2AP Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:100-1:300 Background:This gene encodes a scaffolding molecµLe that regµLates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins throµgh mµLtiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerµLar disease. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CD2AP Research Areas:Signal transduction