ELISA CDCA2 anti-

Quantity :100µL Clone Number: Aliases:CDCA2Cell division cycle-associated protein 2 antibody; Recruits PP1 onto mitotic chromatin at anaphase protein antibody; Repo-Man antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q69YH5 Immunogen:SyntheQuantityd peptide derived from C-terminal of CDCA2. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:RegµLator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture throµgh anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates. Walker M.G., Curr. Cancer Drµg Targets 1:73-83(2001). Ota T., Genet. 36:40-45(2004). Olsen J.V., Cell 127:635-648(2006). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CDCA2 Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology;Metabolism