ELISA ADRBK1 (Ab-86) anti-

Quantity :100µL Clone Number: Aliases:ADRBK1 antibody; Adrenergic beta receptor kinase 1 antibody; ARBK1_ antibody; BARK antibody; BARK1 antibody; Beta adrenergic receptor kinase 1 antibody; Beta ARK 1 antibody; Beta ARK1 antibody; Beta-adrenergic receptor kinase 1 antibody; Beta-ARK-1 antibody; FLJ16718 antibody; G protein coupled receptor kinase 2 antibody; G-protein coupled receptor kinase 2 antibody; GRK2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P25098 Immunogen:SyntheQuantityd peptide derived from N-terminal of ADRBK1. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regµLator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. Benovic J.L., FEBS Lett. 283:122-126(1991). Chuang T.T., J. Biol. Chem. 267:6886-6892(1992). Penn R.B., J. Biol. Chem. 269:14924-14930(1994). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:GRK2 Research Areas:Neuroscience;Signal transduction