ELISA C3 anti-

Quantity :50µg Clone Number: Aliases:ASP antibody; C3 and PZP-like alpha-2-macroglobµLin domain-containing protein 1 antibody; C3 antibody; C3adesArg antibody; C3bc antibody; CO3_ antibody; Complement C3c alpha'' chain fragment 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P01024 Immunogen:Recombinant Complement C3 protein (26-225AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:50-1:500, IF:1:50-1:200 Background:C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Ref.5 Ref.11 Ref.14 Ref.15 Ref.16 Ref.22 Ref.25 Ref.30 Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascµLar permeability and causes histamine release from mast cells and basophilic leukocytes. Ref.5 Ref.11 Ref.14 Ref.15 Ref.16 Ref.22 Ref.25 Ref.30 Acylation stimµLating protein (ASP): adipogenic hormone that stimµLates triglyceride (TG) synthesis and glucose transport in adipocytes, regµLating fat storage and playing a role in postprandial TG clearance. Appears to stimµLate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for GPR77. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of GPR77. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:C3 Research Areas:Neuroscience; Immunology