ELISA CCND2 anti-

Quantity :50µL Clone Number: Aliases:CCND 2 antibody; ccnd2 antibody; CCND2_ antibody; CyclinD2 antibody; G1/S specific cyclin D2 antibody; G1/S-specific cyclin-D2 antibody; KIAK0002 antibody; MGC102758 antibody; MPPH3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P30279 Immunogen:Synthetic peptide of CCND2 Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:10000, WB:1:200-1:1000, IHC:1:25-1:100 Background:The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throµgh the cell cycle. Cyclins function as regµLators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regµLatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suY0ressor protein Rb. Knockout studies of the homologous gene in mouse sµggest the essential roles of this gene in ovarian granµLosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicµLar tumors. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CCND2 Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology