ELISA CDH5 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:7B 4 antibody; 7B4 antibody; 7B4 antigen antibody; CADH5_ antibody; Cadherin 5 antibody; Cadherin 5 type 2 antibody; Cadherin 5, type 2 (vascµLar endothelium) antibody; Cadherin 5, type 2, VE cadherin (vascµLar epithelium) antibody; cadherin, vascµLar endothelial antibody; cadherin, vascµLar endothelial, 1 antibody; Cadherin-5 antibody; Cadherin5 antibody; CD 144 antibody; CD144 antibody; CD144 antigen antibody; CDH 5 antibody; CDH5 antibody; CDH5 protein antibody; Endothelial specific cadherin antibody; FLJ17376 antibody; OTTHUMP00000174777 antibody; VascµLar endothelial cadherin antibody; VascµLar epithelium cadherin antibody; VE Cad antibody; VE-cadherin antibody; VEC antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P33151 Immunogen:Recombinant Cadherin-5 protein (349-569AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology throµgh control of the cohesion and organization of the intercellµLar junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascµLar lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CDH5 Research Areas:Cancer; CardiovascµLar; Signal transduction