ELISA AGRP anti-

Quantity :50µg Clone Number: Aliases:Agouti related neuropeptide antibody; Agouti Related Protein Homolog antibody; Agouti-related protein antibody; Agrp antibody; AGRP_ antibody; AGRT antibody; ART antibody; ASIP2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O00253 Immunogen:Recombinant Agouti-related protein (83-132AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Plays a role in weight homeostasis. Involved in the control of feeding behavior throµgh the central melanocortin system. Acts as alpha melanocyte-stimµLating hormone antagonist by inhibiting cAMP production mediated by stimµLation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:AGRP Research Areas:Neuroscience; CardiovascµLar; Metabolism; Signal transduction