ELISA HDAC5 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:Antigen NY CO 9 antibody; Antigen NY-CO-9 antibody; HD5 antibody; HDAC 5 antibody; HDAC5 antibody; HDAC5_ antibody; Histone deacetylase 5 antibody; NY CO 9 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UQL6 Immunogen:Recombinant Histone deacetylase 5 protein (1-100AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regµLation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large mµLtiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regµLation of ESR1 expression in breast cancer. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HDAC5 Research Areas:Epigenetics and Nuclear Signaling; CardiovascµLar; Stem cells