ELISA E2F6 anti-

Quantity :50µL Clone Number: Aliases:E2F 6 antibody; E2F binding site modµLating activity protein antibody; E2F transcription factor 6 antibody; E2F transcription factor 6 isoform 1 antibody; E2F-6 antibody; E2F6 antibody; E2F6_ antibody; EMA antibody; MGC111545 antibody; Transcription factor E2F6 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O75461 Immunogen:Recombinant Transcription factor E2F6 protein (1-281AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins throµgh the E2 recognition site, 5\\\'-TTTC[CG]CGC-3\\\'. Has a preference for the 5\\\'-TTTCCCGC-3\\\' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regµLate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:E2F6 Research Areas:Epigenetics and Nuclear Signaling