ELISA CBX4 anti-

Quantity :50µL Clone Number: Aliases:CBX 4 antibody; CBX4 antibody; Cbx4 chromobox homolog 4 (Drosophila Pc class) antibody; CBX4_ antibody; Chromobox homolog 4 (Pc class homolog; Drosophila) antibody; Chromobox homolog 4 antibody; Chromobox protein homolog 4 antibody; E3 SUMO protein ligase CBX 4 antibody; E3 SUMO protein ligase CBX4 antibody; E3 SUMO-protein ligase CBX4 antibody; hPc 2 antibody; hPc2 antibody; NBP 16 antibody; NBP16 antibody; NS5ATP1 binding protein 16 antibody; Pc 2 antibody; Pc class 2 homolog antibody; Pc class homolog antibody; Pc class homolog Drosophila antibody; PC2 antibody; Polycomb 2 homolog antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O00257 Immunogen:Recombinant E3 SUMO-protein ligase CBX4 protein (401-560AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:E3 SUMO-protein ligase which facilitates SUMO1 conjµgation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regµLates p53/TP53 transcriptional activation resµLting in p21/CDKN1A expression. Monosumoylates ZNF131. Component of a Polycomb group (PcG) mµLtiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throµghout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A \\\'Lys-119\\\', rendering chromatin heritably changed in its expressibility. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CBX4 Research Areas:Epigenetics and Nuclear Signaling