ELISA APTX Antibody, Biotin
Quantity :50µg
Clone Number:
Aliases:AOA 1 antibody; AOA antibody; AOA1 antibody; Aprataxin antibody; Aprataxin homolog antibody; Aptx antibody; APTX_ antibody; Ataxia 1 early onset with hypoalbuminemia antibody; Ataxia1 early onset with hypoalbuminemia antibody; AXA 1 antibody; AXA1 antibody; EAOH antibody; EOAHA antibody; FHA HIT antibody; FHA-HIT antibody; FLJ20157 antibody; Forkhead associated domain histidine triad like antibody; Forkhead associated domain histidine triad like protein antibody; Forkhead-associated domain histidine triad-like protein antibody; MGC1072 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q7Z2E3
Immunogen:Recombinant Aprataxin protein (92-161AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA
Background:DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5\'-phosphate termini, resµLting in the production of 5\'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5\'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Biotin
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:APTX
Research Areas:Epigenetics and Nuclear Signaling