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ELISA ALOX15B anti-

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Quantity :50µL Clone Number: Aliases:15 Lipoxygenase 2 antibody; 15 LO 2 antibody; 15 LOX 2 antibody; 15-lipoxygenase 2 antibody; 15-LOX-2 antibody; 15-LOX-B antibody; Alox15b antibody; Arachidonate 15 lipoxygenase second type antibody; Arachidonate 15 lipoxygenase type II antibody; Arachidonate 15-lipoxygenase B antibody; Arachidonate 15-lipoxygenase type II antibody; LX15B_ antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O15296 Immunogen:Recombinant Arachidonate 15-lipoxygenase B protein (1-200AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 Background:Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regµLate progression throµgh the cell cycle and cell proliferation. May also regµLate cytokine secretion by macrophages and therefore play a role in the immune response. May also regµLate macrophage differentiation into proatherogenic foam cells. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ALOX15B Research Areas:Cancer; CardiovascµLar; Metabolism; Signal transduction

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