ELISA CD14 Monoclonal Antibody,Purified

Quantity :100µL Clone Number: Aliases: Product Type:Monoclonal Antibody Immunogen Species: UniProt ID:P08571 Immunogen:Recombinant Protein Raised in:Mouse Reactivity: Tested Applications:ELISA,IF,FC;Recommended dilution:IF:1:100-1:200 Background:4AW4 reacts with CD14, a 53-55 kDa molecµLe. CD14 is a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS-endotoxin) and serum LPS-binding protein (LPB). CD14 antigen has a strong presence on the surface of monocytes/macrophages, is weakly expressed on granµLocytes, but not expressed by myeloid progenitor cells. CD14 functions as a receptor for endotoxin; when the monocytes become activated they release cytokines such as TNF, and up-regµLate cell surface molecµLes including adhesion molecµLes.This clone is cross reactive with non- primate.1. Knapp, W et al., eds. (1989) Leucocyte Typing IV : White Cell Differentiation Antigens, Oxford University Press, New York.2. Makgoba, MW et al., (1988) Nature 331: 86-883. Boyd. AW et al. (1989) Blood 73: 1896-1903 Clonality:Monoclonal Isotype:IgG1 Purification Method:Affinity purified Conjµgate:Non-conjµgated Buffer:Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CD14 Research Areas:Immunology;Stem cells