ELISA BRAP Monoclonal anti-

Quantity :100µL Clone Number: Aliases:3010002G07Rik; BRAP2; BRCA1 associated protein; EC 6.3.2.; Galectin 2 binding protein; IMP; Impedes mitogenic signal propagation; Renal carcinoma antigen NY REN 63; RING finger protein 52; RNF52; zgc:92894. Product Type:Monoclonal Antibody Immunogen Species: UniProt ID:Q7Z569 Immunogen:Purified recombinant BRAP protein fragments expressed in E.coli. Raised in:Mouse Reactivity: Tested Applications:ELISA,WB;Recommended dilution:WB:1:500-1:5000 Background:Negatively regµLates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resµLting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regµLating nuclear transport. Clonality:Monoclonal Isotype:IgG1 Purification Method:Affinity purified Conjµgate:Non-conjµgated Buffer:Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BRAP Research Areas:Epigenetics and Nuclear Signaling;Signal transduction