ELISA CD4 Monoclonal Antibody,APC

Quantity :100µL Clone Number: Aliases: Product Type:Monoclonal Antibody Immunogen Species: UniProt ID:P01730 Immunogen:Recombinant Protein Raised in:Mouse Reactivity: Tested Applications:ELISA,IF,FC;Recommended dilution:IF:1:100-1:200 Background:CD4, also known as T4, is a 55 kD single chain transmembrane glycoprotein and belongs to immunoglobµLin superfamily. CD4 is found on most thymocytes, a subset of T cells and at low level on monocytes/macrophages.CD4 is a co-receptor involved in immune response (co-receptor activity in binding to MHC class II molecµLes) and HIV infection (CD4 is primary receptor for HIV-1 surface glycoprotein gp120). CD4 regµLates T-cell activation, T/B-cell adhesion, T-cell diferentiation, T-cell selection and signal transduction.1. Ledbetter, J et al. (1981) J Exp Med 153:310-323.2. Haynes , B et al. (1986) Leukocyte Typing II: T lymphocytes. New York: Sprimger-Verlag; 3-30.3. Clevers H et al. (1988). Ann Rev Immunol 6 : 629-662.4. Barclay, N et al. (1993). The Leucocyte Factsbook. Academic Press. San Diego. Clonality:Monoclonal Isotype:IgG2b Purification Method:Affinity purified Conjµgate:Non-conjµgated Buffer:Phosphate-buffered solution, pH7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CD4 Research Areas:Immunology;Stem cells