ELISA c-MYC anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:MYC contains one basic helix-loop-helix(bHLH) domain. This protein is a mµLtifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellµLar transformation. It functions as a transcription factor that regµLates transcription of specific target genes. It seems to activate the transcription of growth-related genes. It binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. This antibody is a rabbit polyclonal antibody raised against recombinant protein of MYC.The 50kDa band recognized by antibody is the native form of MYC, while the other bands, between 60-70kDa, are the phosphorylated form of MYC [PMID: 12189186] Immunogen:v-myc myelocytomatosis viral oncogene homolog(avian) Synonyms:BHLHe39, c Myc, c-Myc, MRTL, MYC, Myc proto oncogene protein, Proto oncogene c Myc, Transcription factor p64 Observed MW:62-65 kDa, 50 kDa Uniprot ID:P01106 Reactivity:, Mouse Tested Application:ELISA, WB, IP, IHC Recommended dilution:WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:50-1:200 Gene ID: Research Area:Epigenetics, Metabolism, Immunology, Cancer, Neuroscience, Stem Cells, Cell Division and Proliferation