ELISA c-Met anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:c-Met(also named as MET or HGFR) is a receptor tyrosine kinase that transduces signals from the extracellµLar matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. c-Met regµLates many physiological processes including proliferation, scattering, morphogenesis and survival. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disµLfide linked to form the mature receptor. Overexpression and/or mutation of c-Met has been reported in various malignancies, including lung cancer, breast cancer, head and neck cancer, gastric cancer, colorectal cancer, bladder cancer, uterine cervix carcinoma, and esophageal carcinoma, c-Met coµLd serve as an important therapeutic target(PMID: 26036285). This antibody recognizes the N-term of c-Met. Immunogen:met proto-oncogene(hepatocyte growth factor receptor) Synonyms:AUTS9, c-Met, HGF receptor, HGF/SF receptor, HGFR, MET, Proto oncogene c Met, RCCP2, Scatter factor receptor, SF receptor, Tyrosine protein kinase Met Observed MW:150 kDa Uniprot ID:P08581 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500-1:1000; IHC: 1:50-1:200 Gene ID:4233 Research Area:Epigenetics, Metabolism, Immunology, Cancer, Neuroscience, Stem Cells, Cell Division and Proliferation