ELISA CBX5 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)
Background:This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore throµgh interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. MµLtiple alternatively spliced variants, encoding the same protein, have been identified.
Immunogen:chromobox homolog 5 (HP1 alpha homolog, Drosophila)
Synonyms:HP1A
Observed MW:23 kDa
Uniprot ID:P45973
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB, IHC
Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Gene ID:23468
Research Area:Epigenetics, Metabolism