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ELISA CAMKK2 anti-

https://research.gentaur.com/web/image/product.template/14054/image_1920?unique=362af79
Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Calcium/calmodµLin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellµLar processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodµLin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase(AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimµLated in response to Ca(2+) signals(By similarity). Seems to be involved in hippocampal activation of CREB1(By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching. Immunogen:calcium/calmodµLin-dependent protein kinase kinase 2, beta Synonyms:CAMKKB, KIAA0787 Observed MW:55-60 kDa Uniprot ID:Q96RR4 Reactivity:, Mouse Tested Application:ELISA, WB, IF, IHC Recommended dilution:WB: 1:500-1:2000; IF: 1:20-1:200; IHC: 1:20-1:200 Gene ID:10645 Research Area:Neuroscience, Signal Transduction, Metabolism

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470,00 €

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