ELISA C5AR1 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a(PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellµLar N-terminus, and a second site in the transmembrane region which activates downstream signaling events(PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimµLates chemotaxis, granµLe enzyme release, intracellµLar calcium release and superoxide anion production(PubMed:10636859, PubMed:15153520).
Immunogen:complement component 5a receptor 1
Synonyms:C5AR, C5R1
Observed MW:45-50 kDa
Uniprot ID:P21730
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB, IHC, IF, IP
Recommended dilution:WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Gene ID:728
Research Area:Signal Transduction, Metabolism, Immunology