ELISA BVES anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Cell adhesion molecµLe involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regµLation of the tight junction(TJ) paracellµLar permeability barrier in epithelial cells(PubMed:16188940). Plays a role in VAMP3-mediated vesicµLar transport and recycling of different receptor molecµLes throµgh its interaction with VAMP3. Plays a role in the regµLation of cell shape and movement by modµLating the Rho-family GTPase activity throµgh its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regµLation of cell spreading(By similarity). Important for the maintenance of cardiac function. Plays a regµLatory function in heart rate dynamics mediated, at least in part, throµgh cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density(PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury. Immunogen:blood vessel epicardial substance Synonyms:BVES, HBVES, POP1, POPDC1, Popeye protein 1 Observed MW:41-70 kDa Uniprot ID:Q8NE79 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:100-1:1000; IHC: 1:20-1:200 Gene ID:11149 Research Area:Stem Cells, Developmental biology