ELISA BUB3 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubµLe(K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. RegµLates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome(APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1. Immunogen:budding uninhibited by benzimidazoles 3 homolog(yeast) Synonyms: Observed MW: Uniprot ID:O43684 Reactivity:, Mouse, Rat Tested Application:ELISA, IF Recommended dilution:IF: 1:20-1:200 Gene ID:9184 Research Area:Cell Division and Proliferation