ELISA CDC42 anti-

Quantity :50µL Clone Number:3C3 Aliases:Cell division control protein 42 homolog (G25K GTP-binding protein), CDC42 Product Type:Recombinant Antibody Immunogen Species:Homo sapiens () UniProt ID:P60953 Immunogen:A syntheQuantityd peptide derived from CDC42 Raised in: Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200 Background:Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regµLate cellµLar responses. Involved in epithelial cell polarization processes. RegµLates the bipolar attachment of spindle microtubµLes to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration. Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons. Facilitates filopodia formation upon DOCK11-activation (By similarity). Clonality:Monoclonal Isotype:Rabbit IgG Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CDC42 Research Areas:Epigenetics and Nuclear Signaling; Cancer; Cell biology; Signal transduction