ELISA CD146 anti-

Quantity :50µL Clone Number:8A10 Aliases:Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, Melanoma cell adhesion molecµLe, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen, CD146, MCAM, MUC18 Product Type:Recombinant Antibody Immunogen Species: UniProt ID:P43121 Immunogen:A syntheQuantityd peptide Raised in: Reactivity: Tested Applications:ELISA, WB, IHC, IF, FC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500, IF:1:30-1:200 Background:Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellµLar junctions in vascµLar tissue. Its expression may allow melanoma cells to interact with cellµLar elements of the vascµLar system, thereby enhancing hematogeneous tumor spread. CoµLd be an adhesion molecµLe active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellµLar calcium concentration. Clonality:Monoclonal Isotype:Rabbit IgG Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:MCAM Research Areas:Immunology